Basel Biometric Section of the Austro-Swiss Region of the International Biometric Society
Willi Sauerbrei, Patrick Royston, Benjamin Kasenda and Matthias Briel, A method for IPD meta-analysis of treatment-covariate interaction with a continuous predictor in randomised trials
Actelion Pharmaceuticals, Hegenheimermattweg 91, 4123 Allschwil (direction PDF, building map GIF).
Agenda BBS Seminar Benefit-Risk & Comparative Effectiveness PDF
Andrea Beyer, Understanding the risk tolerance of regulatory assessors in Europe: the role of quantitative models in risk communication
Christoph Dierig and Richard Nixon, A case study using the BRAT framework for benefit risk assessment
Christian Hove Rasmussen, Benefit-risk assessment from a clinical point of view: a structured approach with focus on transparency, clinical significance and visualization
Ralf Bender, Biometrical requirements in (early) benefit assessments
Fred Sorenson, Benefit-risk assessment and comparative effectiveness research: are they really converging?
Agenda BBS Seminar Emerging Topics in Pharmaceutical Statistics PDF
Stephen A. Julious, Sample sizes for multiple must-win trials
Eric Derobert, A parameterized strategy of gatekeeping, keeping untouched the probability of having at least one significant result
Lisa Hampson, Group sequential tests for delayed responses
Agenda BBS Seminar Experiences in the Development and Implementation of Flexible Designs PDF
Agenda BBS Seminar PDF
Agenda BBS Fall Conference 2011 Current Topics in Pharmaceutical Statistics:
Dose Finding and Multiregional Trials PDF
Andy Grieve, Dose Selection in Drug Development: What Can Go Wrong? Can we put it Right?
Didier Renard, Use of modeling & simulation to support design and analysis of a new dose and regimen finding study
Björn Bornkamp, On the efficiency of two-stage adaptive designs
H.M. James Hung, Planning and Analyzing Multi-regional Clinical Trials: A Regulatory Perspective
Philip Hougaard, Global drug development strategies
Jørgen Seldrup, Designing clinical trials in a multiregional regulatory environment
Kevin J. Carroll, Consistency of treatment effect across regions in a multi-regional trial: reasonable goal or unrealistic requirement?
Agenda BBS Seminar Improving Statistical Graphics and BBS General Meeting PDF
Fabrice Bancken, General Principles, Illustrations and Wiki Resources for Improving Statistical Graphs
Further reading:
Ramon Saccilotto, Tutorial for the ggplot2 plotting system for R (based on the book by Hadley Wickham), R code
Agenda BBS Seminar Quantitative Benefit-Risk: What Matters to Whom and How? – Getting the Values and Weights Right PDF
INTRODUCTION
John Ferguson, Structured Benefit-Risk Optimization (BRO): A Framework Quantitative Decision Support Tools
Gordon Francis, Clinical Perspective on Benefit-Risk Assessments
Lawrence Phillips, Quantitative Benefit-Risk: Determining Values & Assessing Weights
Andrea Beyer, Beyond the Probability of Risk: Measuring Perception, Preferences and Values for Health States
